Lecture Handouts

All handouts can be downloaded as pdf files. The handouts are listed in the order in which their content is discussed in class. In case you encounter problems downloading or viewing these files please let me know as soon as possible by e-mail.

Introduction to enzymology and review of amino acids and proteins
Visualization of proteins, and methods of structure determination
Enzyme/protein isolation and purification
Thermodynamic aspects of enzyme function
Principal mechanisms of enzyme catalysis
Enzyme kinetics: Michaelis-Menten kinetics
Enzyme kinetics: Inhibition, multisubstrate reactions, allosteric and kinetic isotope effects, stopped-flow
Excel Solver: Tutorial video
Coenzymes
Metalloenzymes
Isozymes
Abzymes and Ribozymes
Enzymes in industrial applications
Clinical enzymology